Oncological emergencies: syndrome of inappropriate antidiuretic hormone secretion (SIADH).
نویسندگان
چکیده
Excessive secretion of vasopressin in the course of Syndrome of Inappropriate Antidiuretic Hormone Secretion is a common cause of hyponatremia in cancer patients. Clinical symptoms depend on the cause, rate of change of sodium level and their absolute values. Treatment options include fluid restrictions, intravenous administration of hypertonic sodium chloride solutions, loop diuretics and vaptans. The sodium level should not be adjusted too fast, because it may lead to irreversible brain damage. The article presents pathophysiology, diagnostics and recommendations of management of this oncological emergency.
منابع مشابه
Psychosis followed by Lung Cancer with Syndrome of Inappropriate Secretion of Antidiuretic Hormone (SIADH): A Case Report
Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) refers to the excessive release of antidiuretic hormone (ADH) resulting in water retention, dilutional hyponatremia and urinary sodium waste, and some other clinical manifestations. Causes of SIADH include many disease conditions, some medications and nicotine. The present study reports a case of psychosis followed by lung canc...
متن کاملSyndrome of inappropriate antidiuretic hormone secretion.
The syndrome of inappropriate antidiuretic hormone secretion (SIADH) results from the aberrant or sustained secretion of the antidiuretic hormone. Classic manifestations include water retention, hyponatremia, and hypo-osmolality of the serum. Treatment is aimed at differentiating SIADH from other causes of hyponatremia, determining the underlying disorder, and alleviating the excessive water re...
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Neuromyelitis optica (NMO) has been reported to be associated with endocrinopathies, such as amenorrhea, galactorrhea, and diabetes mellitus. However, its association with the syndrome of inappropriate antidiuretic hormone secretion (SIADH) is extremely rare. We herein report an adult case of NMO with SIADH in a female Chinese patient. The patient was aquaporin-4 antibody positive, and her hypo...
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SYNDROME OF INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION ASSOCIATED WITH SMALL CELLS LUNG CANCER WITH BONE METASTASIS (ABSTRACT): A patient with a bone metastasis developed a asymptomatic hyponatremia, with all features of the Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH). The event was interpreted as a consequence of ADH release due to to primary cancer located in the lungs ...
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ورودعنوان ژورنال:
- Przeglad lekarski
دوره 71 10 شماره
صفحات -
تاریخ انتشار 2014